The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2017
Filed:
Sep. 30, 2016
Applicant:
Promega Corporation, Madison, WI (US);
Inventors:
Jessica Kelts, Flint, MI (US);
Poncho Meisenheimer, San Luis Obispo, CA (US);
John Shultz, Verona, WI (US);
Assignee:
PROMEGA CORPORATION, Madison, WI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/533 (2006.01); C07D 417/14 (2006.01); C07D 493/10 (2006.01); C07D 495/04 (2006.01); C09B 11/08 (2006.01); C09B 11/24 (2006.01); C09B 23/08 (2006.01);
U.S. Cl.
CPC ...
G01N 33/533 (2013.01); C07D 417/14 (2013.01); C07D 493/10 (2013.01); C07D 495/04 (2013.01); C09B 11/08 (2013.01); C09B 11/24 (2013.01); C09B 23/083 (2013.01);
Abstract
The invention provides compounds and methods for site-specifically labeling proteins with cyanobenzothiazole derivatives of formula I. For example, the invention provides methods for labeling the N-terminus of a protein that terminates with a cysteine residue. The invention also provides methods for isolating an N-terminally labeled protein and methods for detecting an N-terminally labeled protein.