The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2017
Filed:
Oct. 20, 2011
Jin Sook Chang, Seoul, KR;
Jae Hyun JO, Seoul, KR;
Hyun AE Bae, Incheon, KR;
Byeong Cheol Song, Uiwang-si, KR;
Sol Kim, Seoul, KR;
Hye Won Kim, Seongnam-si, KR;
Hye Won Um, Suwon-si, KR;
Sung Hoo Jhon, Seoul, KR;
Yong Uk Shin, Yongin-si, KR;
Eun Bin Yang, Seoul, KR;
Kyoung Min Lee, Seoul, KR;
Soo an Shin, Seoul, KR;
Jin Sook Chang, Seoul, KR;
Jae Hyun Jo, Seoul, KR;
Hyun Ae Bae, Incheon, KR;
Byeong Cheol Song, Uiwang-si, KR;
Sol Kim, Seoul, KR;
Hye Won Kim, Seongnam-si, KR;
Hye Won Um, Suwon-si, KR;
Sung Hoo Jhon, Seoul, KR;
Yong Uk Shin, Yongin-si, KR;
Eun Bin Yang, Seoul, KR;
Kyoung Min Lee, Seoul, KR;
Soo An Shin, Seoul, KR;
CJ CHEILJEDANG CORPORATION, Seoul, KR;
Abstract
The present invention provides methods for the production of cysteine or derivates thereof by culturing a microorganism having reduced activity of endogenous phosphoserine phosphatase and the activity of PhnC, PhnD, and PhnE is reduced, and enhanced activity of phosphoglycerate dehydrogenase and/or phosphoserine aminotransferase. The O-phosphoserine produced by such an organism can then be reacted with a sulfide in the presence of a sulfydrylase or a microorganism expressing a sulfhydrylase to produce cysteine or a derivative thereof. Microorganisms having these reduced and enhanced properties noted above are also provided herein.