The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2017
Filed:
Jul. 03, 2013
Applicant:
Albert Einstein College of Medicine of Yeshiva University, Bronx, NY (US);
Inventors:
Matthew Levy, New Rochelle, NY (US);
Deborah Palliser, Bronx, NY (US);
Brian Christopher Wengerter, Bronx, NY (US);
Steven Craig Almo, Pelham, NY (US);
Assignee:
Albert Einstein College of Medicine, Inc., Bronx, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/115 (2010.01); A61K 39/385 (2006.01); A61K 47/48 (2006.01); A61K 39/00 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/115 (2013.01); A61K 39/385 (2013.01); A61K 47/48092 (2013.01); A61K 2039/6025 (2013.01); C12N 15/1138 (2013.01); C12N 2310/14 (2013.01); C12N 2310/16 (2013.01); C12N 2310/3513 (2013.01); C12N 2320/32 (2013.01);
Abstract
A composition is provided comprising an oligonucleotide aptamer conjugated to an antigen, wherein the aptamer is directed against a cell-surface target of an antigen-presenting cell. Also provided are methods of delivering an antigen to a dendritic cell and of eliciting an immune response in a subject.