The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2017
Filed:
Jun. 29, 2015
Applicants:
Excaliard Pharmaceuticals, Inc., New York, NY (US);
Ionis Pharmaceuticals, Inc., Carlsbad, CA (US);
Inventors:
Nicholas M. Dean, Encinitas, CA (US);
J. Gordon Foulkes, Encinitas, CA (US);
Niall O'Donnell, St. Louis, MO (US);
C. Frank Bennett, Carlsbad, CA (US);
Susan M. Freier, San Diego, CA (US);
Assignees:
Excaliard Pharmaceuticals, Inc., New York, NY (US);
Ionis Pharmaceuticals, Inc., Carlsbad, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/70 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/113 (2010.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1136 (2013.01); C12N 15/113 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01); C12N 2310/3231 (2013.01); C12N 2310/3341 (2013.01); C12N 2310/341 (2013.01); C12N 2310/346 (2013.01); C12N 2320/30 (2013.01);
Abstract
This invention provides compounds which comprise modified oligonucleotides capable of inhibitory expression of connective tissue factor and composition containing same as well as methods of treating hyperprolific disorders and fibrotic diseases, and of reducing scarring resulting from wound healing using such compounds.