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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9688978 B1

PDFFull Text
Date of Patent:
Jun. 27, 2017

Filed:

Dec. 27, 2012

Aspartyl-trna synthetase-fc conjugates

Applicant:

Atyr Pharma, Inc., San Diego, CA (US);

Inventors:

Ying Ji Buechler, Carlsbad, CA (US);

Chi-Fang Wu, San Diego, CA (US);

Ryan Andrew Adams, San Diego, CA (US);

Jeffrey D. Watkins, Encinitas, CA (US);

John D. Mendlein, Encinitas, CA (US);

Assignee:

aTyr Pharma, Inc., San Diego, CA (US);

Attorney:

Cooley LLP

Primary Examiner:

Kagnew H Gebreyesus

Int. Cl.
CPC ...
C12N 9/96 (2006.01); C07K 14/00 (2006.01); G01N 33/68 (2006.01); C12N 9/00 (2006.01); C07K 16/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/93 (2013.01); C07K 16/00 (2013.01); C12Y 601/01012 (2013.01); A61K 38/00 (2013.01); C07K 2319/02 (2013.01); C07K 2319/21 (2013.01); C07K 2319/30 (2013.01); C07K 2319/50 (2013.01); C12Y 601/01002 (2013.01);
Abstract

The present invention provides aspartyl-tRNA synthetase and Fc region conjugate polypeptides (DRS-Fc conjugates), such as DRS-Fc fusion proteins, compositions comprising the same, and methods of using such conjugates and compositions for treating or diagnosing a variety of conditions. The DRS-Fc conjugates of the invention have improved controlled release properties, stability, half-life, and other pharmacokinetic and biological properties relative to corresponding, unmodified DRS polypeptides.

Find Patent Forward Citations

Buechler, Ying. (2017). Aspartyl-trna synthetase-fc conjugates (U.S. Patent No. 9688978). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9688978

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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