The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2017
Filed:
Dec. 27, 2012
Atyr Pharma, Inc., San Diego, CA (US);
Ying Ji Buechler, Carlsbad, CA (US);
Chi-Fang Wu, San Diego, CA (US);
Ryan Andrew Adams, San Diego, CA (US);
Jeffrey D. Watkins, Encinitas, CA (US);
John D. Mendlein, Encinitas, CA (US);
aTyr Pharma, Inc., San Diego, CA (US);
Abstract
The present invention provides aspartyl-tRNA synthetase and Fc region conjugate polypeptides (DRS-Fc conjugates), such as DRS-Fc fusion proteins, compositions comprising the same, and methods of using such conjugates and compositions for treating or diagnosing a variety of conditions. The DRS-Fc conjugates of the invention have improved controlled release properties, stability, half-life, and other pharmacokinetic and biological properties relative to corresponding, unmodified DRS polypeptides.