The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 27, 2017

Filed:

Jun. 26, 2012
Applicants:

Ian B. Copland, Decatur, GA (US);

Jacques Galipeau, Atlanta, GA (US);

Inventors:

Ian B. Copland, Decatur, GA (US);

Jacques Galipeau, Atlanta, GA (US);

Assignees:

Emory University, Atlanta, GA (US);

Children's Healthcare of Atlanta, Inc., Atlanta, GA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/14 (2015.01); C12N 5/00 (2006.01); C12N 5/0775 (2010.01); A61K 38/18 (2006.01); A61K 35/19 (2015.01); A61L 15/40 (2006.01); A61L 15/44 (2006.01); A61L 17/00 (2006.01); A61L 24/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0675 (2013.01); A61K 35/19 (2013.01); A61K 38/1858 (2013.01); A61L 15/40 (2013.01); A61L 15/44 (2013.01); A61L 17/005 (2013.01); A61L 24/0005 (2013.01); A61L 24/0015 (2013.01); C12N 5/0018 (2013.01); C12N 5/0662 (2013.01); C12N 5/0663 (2013.01); C12N 5/0664 (2013.01); C12N 5/0665 (2013.01); C12N 5/0666 (2013.01); C12N 5/0667 (2013.01); C12N 5/0668 (2013.01); A61L 2300/406 (2013.01); C12N 2502/115 (2013.01);
Abstract

In certain embodiments, this disclosure describes compositions comprising platelet lysates depleted of fibrinogen. In a further embodiment, the composition further comprises a cell culture medium component. This disclosure also provides a method for preparing the composition, comprising the steps of (a) lysing platelets providing a lysate; (b) removing cell debris; and (c) depleting fibrinogen by forming a removable mass by adding a metal salt such as calcium chloride. Furthermore, the disclosure also describes the product produced using said method.


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