The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2017
Filed:
Mar. 02, 2015
Applicant:
Abbvie, Inc., North Chicago, IL (US);
Inventors:
Chen Wang, Shrewsbury, MA (US);
Germano Coppola, Shrewsbury, MA (US);
Chris Chumsae, North Andover, MA (US);
Assignee:
AbbVie Inc., North Chicago, IL (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/24 (2006.01); C07K 14/525 (2006.01); A61K 39/395 (2006.01); C07K 16/06 (2006.01); C07K 1/16 (2006.01);
U.S. Cl.
CPC ...
C07K 16/241 (2013.01); A61K 39/39591 (2013.01); C07K 14/525 (2013.01); C07K 16/065 (2013.01); C07K 1/165 (2013.01); C07K 2317/565 (2013.01);
Abstract
The present invention relates to low acidic species (AR) compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods for producing such low AR compositions using displacement chromatography. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNFα is detrimental, are also provided.