The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 27, 2017

Filed:

Apr. 27, 2015
Applicant:

Trellis Bioscience, Llc, Menlo Park, CA (US);

Inventors:

Lawrence M. Kauvar, San Francisco, CA (US);

Stote Ellsworth, Palo Alto, CA (US);

William Usinger, Lafayette, CA (US);

Krista Maureen McCutcheon, Burlingame, CA (US);

Ying-Ping Jiang, Lafayette, CA (US);

Fen Zhang, San Francisco, CA (US);

Bo Chen, Daly City, CA (US);

Gizette Sperinde, El Granada, CA (US);

Minha Park, Brisbane, CA (US);

Orit Foord, Foster City, CA (US);

Assignee:

Trellis Bioscience, LLC, Menlo Park, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/08 (2006.01); C07K 16/46 (2006.01); A61K 39/245 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/088 (2013.01); A61K 39/245 (2013.01); C07K 16/468 (2013.01); A61K 2039/505 (2013.01); C07K 16/08 (2013.01); C07K 2317/14 (2013.01); C07K 2317/21 (2013.01); C07K 2317/30 (2013.01); C07K 2317/34 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

Recombinant monoclonal antibodies to human cytomegalovirus (CMV) gB protein are described. The affinities of these antibodies are higher than the best previously reported antibodies. Since high affinity is critical to prevention of virus transfer across the placenta, the invention antibodies are useful as therapeutic and prophylactic agents to prevent or ameliorate effects on the fetus of CMV infection during pregnancy.


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