The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2017
Filed:
Jan. 05, 2015
Stephen Berasi, Arlington, MA (US);
Robert Vincent Martinez, Carlisle, MA (US);
Michael John Cain, Exeter, NH (US);
John Martin Wozney, Hudson, MA (US);
Howard Joel Seeherman, Cambridge, MA (US);
Zong Sean Juo, Cambridge, MA (US);
Valerie Perrine Calabro, Carro, FR;
Christopher Todd Brown, Chelmsford, MA (US);
Stephen Berasi, Arlington, MA (US);
Robert Vincent Martinez, Carlisle, MA (US);
Michael John Cain, Exeter, NH (US);
John Martin Wozney, Hudson, MA (US);
Howard Joel Seeherman, Cambridge, MA (US);
Zong Sean Juo, Cambridge, MA (US);
Valerie Perrine Calabro, Carro, FR;
Christopher Todd Brown, Chelmsford, MA (US);
Wyeth LLC, Madison, NJ (US);
Abstract
The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.