The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 27, 2017

Filed:

Apr. 24, 2013
Applicants:

Bristol-myers Squibb Company, Princeton, NJ (US);

Universite DE Montreal, Montreal, CA;

Inventors:

Jacques Banville, Saint-Hubert, CA;

Roger Rémillard, Napierville, CA;

Edward H. Ruediger, Greenfield Park, CA;

Daniel H. Deon, Montreal, CA;

Marc Gagnon, Ville Saint-Laurent, CA;

Laurence Dubé, Laval, CA;

Julia Guy, Montreal, CA;

Eldon Scott Priestley, Yardley, PA (US);

Shoshana L. Posy, Highland Park, NJ (US);

Brad D. Maxwell, Doylestown, PA (US);

Pancras C. Wong, Plainsboro, NJ (US);

R. Michael Lawrence, Yardley, PA (US);

Michael M. Miller, Pennington, NJ (US);

Assignee:

BRISTOL-MYERS SQUIBB COMPANY, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 513/04 (2006.01); C07D 487/04 (2006.01); C07D 519/00 (2006.01); A61K 45/06 (2006.01); A61K 31/433 (2006.01); A61K 31/4439 (2006.01); A61K 31/454 (2006.01); A61K 31/496 (2006.01); A61K 31/497 (2006.01); A61K 31/5025 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01); A61K 31/553 (2006.01);
U.S. Cl.
CPC ...
C07D 513/04 (2013.01); A61K 31/433 (2013.01); A61K 31/4439 (2013.01); A61K 31/454 (2013.01); A61K 31/496 (2013.01); A61K 31/497 (2013.01); A61K 31/5025 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); A61K 31/553 (2013.01); A61K 45/06 (2013.01); C07D 487/04 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention provides thiazole compounds of Formula I wherein W, Y, R, R, R, R, R, R, X, X, Xand Xare as defined herein, or a stereoisomer, tautomer, pharmaceutically acceptable salt, prodrug ester or solvate form thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of platelet aggregation and thus can be used as medicaments for treating or preventing thromboembolic disorders.


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