The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2017
Filed:
Nov. 26, 2014
Merck Patent Gmbh, Darmstadt, DE;
Dirk Finsinger, Darmstadt, DE;
Margarita Wucherer-Plietker, Messel, DE;
Beatrix Blume, Dossenheim, DE;
Merck Patent GmbH, Darmstadt, DE;
Abstract
The present invention relates to tetrahydro-tetrazolo[1,5-a]pyrazine compounds of formula (I), wherein Rdenotes —R, —CH—Ror —CO—R; Rdenotes Ar, Hetaror C-cycloalkyl; and Rdenotes Ar, Hetaror C-cycloalkyl. These compounds are useful for inhibiting the retinoid-related orphan receptor γ (ROR γ, ROR-gamma) and for the prevention and/or treatment of medical conditions affected by ROR γ activity such as rheumatoid arthritis, multiple sclerosis, psoriasis, ulcerative colitis, asthma, autoimmune hepatitis or type 1 and type 2 diabetes.