The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2017
Filed:
May. 15, 2015
Abbvie Deutschland Gmbh & Co. KG, Wiesbaden, DE;
Hervé Geneste, Ludwigshafen, DE;
Wilfried Hornberger, Ludwigshafen, DE;
Katja Jantos, Ludwigshafen, DE;
Andreas Kling, Ludwigshafen, DE;
Marcel Van Gaalen, Göttingen, DE;
AbbVie Deutschland GmbH & Co. KG, Wiesbaden, DE;
Abstract
The present invention relates to novel substituted oxindole derivatives of the formula I wherein A is a ring selected from phenyl and 6-membered hetaryl containing 1 or 2 nitrogen atoms as ring members, where ring A carries one substituent Rand optionally one substituent R; B is a ring selected from phenyl and a monocyclic or bicyclic heteroaromatic ring containing 1, 2 or 3 heteroatoms selected from O, N and S as ring members, where ring B may carry 1, 2 or 3 substituents R; X, X, Xand X, independently of each other, are selected from —CH—, —O—, —S(O)—, —NH—, —C(O)—, —CHCH—, —CHO—, —OCH—, —S(O)CH—, —CHS(O)—, CHNH—, —NHCH—, —CHC(O)— and C(O)CH—; The present invention also relates to pharmaceutical compositions comprising the novel substituted oxindole derivatives of the formula I, and to their use for the treatment of vasopressin-related disorders.