The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2017
Filed:
Jan. 25, 2017
Celgene Corporation, Summit, NJ (US);
Jasti Venkateswaralu, Hyderabad, IN;
Chinnapillai Rajendiran, Hyderabad, IN;
Nallamaddi Ravikumar Reddy, Hyderabad, IN;
Terrence Joseph Connolly, Warwick, NY (US);
Alexander L. Ruchelman, Cream Ridge, NJ (US);
Jeffrey Eckert, Hazlet, NJ (US);
Anthony Joseph Frank, Easton, PA (US);
Celgene Corporation, Summit, NJ (US);
Abstract
Provided herein are new processes for the preparation of aminosulfone intermediates for the synthesis of 2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, which is useful for preventing or treating diseases or conditions related to an abnormally high level or activity of TNF-α. Further provided herein are processes for the commercial production of (S)-1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethylamine.