The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 27, 2017

Filed:

Aug. 16, 2013
Applicant:

University of Washington Through Its Center for Commercialization, Seattle, WA (US);

Inventors:

Miqin Zhang, Bothell, WA (US);

Chen Fang, Lynwood, WA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/055 (2006.01); A61K 49/18 (2006.01); A61K 9/51 (2006.01); A61K 49/00 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 49/1857 (2013.01); A61K 9/51 (2013.01); A61K 47/48861 (2013.01); A61K 47/48907 (2013.01); A61K 49/0093 (2013.01);
Abstract

Nanoparticle having a poly(beta-amino ester) coating. The poly(beta-amino ester) coating includes one or more therapeutic agents that can be delivered by the particle and one or more anchoring groups that couple the polymer to the nanoparticle's core surface. In certain embodiments, the poly(beta-amino ester) includes one or more polyalkylene oxide groups. The poly(beta-amino ester) can further include a targeting agent to target the nanoparticle to a site of interest and a diagnostic agent that allows for imaging of the particle. Methods for making and using the nanoparticles are also provided.


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