The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2017
Filed:
Aug. 14, 2013
Applicant:
Angiochem Inc., Montreal, CA;
Inventors:
Michel Demeule, Beaconsfield, CA;
Alain Larocque, Saint-Laurent, CA;
Gaoqiang Yang, Montreal, CA;
Sasmita Tripathy, Pierrefonds, CA;
Assignee:
Angiochem Inc., Montreal, CA;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); A61K 47/48 (2006.01); C07K 14/81 (2006.01); A61K 38/10 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48253 (2013.01); A61K 38/10 (2013.01); A61K 47/482 (2013.01); A61K 47/48207 (2013.01); A61K 47/48246 (2013.01); C07K 14/8117 (2013.01);
Abstract
The invention relates to dendrimers conjugated to multiple targeting peptides and one or more therapeutic, diagnostic, or imaging agents for delivery of such agents across the blood-brain barrier and into certain cell types including, cells expressing the LRP-1 receptor. Also described are methods of making compounds that comprise dendrimers conjugated to targeting peptides and therapeutic, diagnostic, or imaging agents.