The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2017
Filed:
May. 07, 2014
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Adah Almutairi, La Jolla, CA (US);
Jagadis Sankaranarayanan, San Diego, CA (US);
Enas Mahmoud, San Diego, CA (US);
Eric Schopf, Solana Beach, CA (US);
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 49/06 (2006.01); A61K 31/711 (2006.01); A61K 38/02 (2006.01); C12N 5/071 (2010.01); A61K 47/34 (2006.01); C08G 69/40 (2006.01); A61K 49/00 (2006.01); A61K 9/51 (2006.01); A61K 49/12 (2006.01); A61K 49/18 (2006.01); B82Y 5/00 (2011.01); B82Y 15/00 (2011.01); B82Y 30/00 (2011.01); B82Y 40/00 (2011.01); C08G 63/672 (2006.01); C08G 63/685 (2006.01); C08G 63/688 (2006.01); C08G 73/06 (2006.01); A61K 48/00 (2006.01); C12N 15/87 (2006.01); A61K 31/713 (2006.01); A61K 38/16 (2006.01); A61K 9/19 (2006.01);
U.S. Cl.
CPC ...
A61K 47/34 (2013.01); A61K 9/5153 (2013.01); A61K 31/713 (2013.01); A61K 38/16 (2013.01); A61K 48/0041 (2013.01); A61K 49/0093 (2013.01); A61K 49/126 (2013.01); A61K 49/128 (2013.01); A61K 49/1818 (2013.01); B82Y 5/00 (2013.01); B82Y 15/00 (2013.01); B82Y 30/00 (2013.01); B82Y 40/00 (2013.01); C08G 63/672 (2013.01); C08G 63/6856 (2013.01); C08G 63/6886 (2013.01); C08G 73/0627 (2013.01); C12N 15/87 (2013.01); A61K 9/19 (2013.01);
Abstract
Nanocarriers are synthesized with polymers that respond to lower pH and/or ROS by being degraded. The compositions may be utilized to selectively deliver payloads within patients by responding to lower pH and/or ROS at localities within the patient. The present invention also features methods of synthesizing nanocarriers that are degraded by lower pH and/or ROS.