The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2017
Filed:
Jul. 23, 2010
Applicants:
Masafumi Shimoda, Providence, RI (US);
Jack R. Wands, East Greenwich, RI (US);
Inventors:
Masafumi Shimoda, Providence, RI (US);
Jack R. Wands, East Greenwich, RI (US);
Assignee:
Rhode Island Hospital, Providence, RI (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 35/00 (2006.01); C12N 5/0784 (2010.01); C12N 9/02 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); C12N 5/0639 (2013.01); C12N 9/0071 (2013.01); A61K 2039/5154 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/545 (2013.01); C12N 2500/90 (2013.01); C12N 2501/22 (2013.01); C12N 2501/23 (2013.01); C12N 2501/24 (2013.01); C12N 2501/52 (2013.01);
Abstract
A vaccine containing AAH-loaded mature dendritic cells for treatment of AAH-expressing tumors in mammalian subjects. A method of producing primed dendritic cells is carried out by contacting isolated dendritic cells with an antigen such as AAH. Following the antigen-contacting step, the dendritic cells are contacted with a combination of cytokines such as GM-CSF and IFN-γ.