The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2017
Filed:
Feb. 03, 2011
Applicant:
Sarah Hamm-alvarez, Los Angeles, CA (US);
Inventor:
Sarah Hamm-Alvarez, Los Angeles, CA (US);
Assignee:
University of Southern California, Los Angeles, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61P 27/02 (2006.01); A61P 37/06 (2006.01); A61K 38/17 (2006.01); A61K 31/436 (2006.01);
U.S. Cl.
CPC ...
A61K 38/17 (2013.01); A61K 31/436 (2013.01);
Abstract
This invention provides a method of inducing a lacrimal acinar cell in a tissue to degrade a secretory vesicle and its content protein or proteins from the trans-Golgi network (TGN) by contacting the cells with an effective amount of an agent that induces autophagy. Also provided is a method for treating a mammal suffering from defective trans-Golgi network-secretory vesicle (TGN-SV) sorting by administering to the mammal an effective amount of an agent that induces autophagy in the tissue having the defective TGN-SV.