The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 27, 2017

Filed:

Jun. 12, 2015
Applicant:

Calithera Biosciences, Inc., South San Francisco, CA (US);

Inventors:

Susanne M. Steggerda, San Francisco, CA (US);

Andrew L. MacKinnon, San Francisco, CA (US);

Mirna L. Rodriguez, San Jose, CA (US);

Dong Zhang, San Jose, CA (US);

Francesco Parlati, San Francisco, CA (US);

Assignee:

Calithera Biosciences, Inc., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/501 (2006.01); A61K 31/517 (2006.01); A61K 31/436 (2006.01); A61K 45/06 (2006.01); A61K 31/502 (2006.01); A61N 5/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/501 (2013.01); A61K 31/436 (2013.01); A61K 31/502 (2013.01); A61K 31/517 (2013.01); A61K 45/06 (2013.01); A61N 5/10 (2013.01);
Abstract

The invention relates to methods of treating cancer, myeloproliferative diseases, or immunological or neurological diseases with a combination of a glutaminase inhibitor and an anticancer agent such as an enzyme inhibitor (such as a kinase inhibitor), a mitotic inhibitor, a DNA-modifying agent, or a cytidine analog. The invention further relates to methods of treating cancer, myeloproliferative diseases, or immunological or neurological diseases that are resistant to one or more anticancer agents.


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