The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 27, 2017

Filed:

May. 26, 2014
Applicant:

Sarah Herzog Memorial Hospital-ezrath Nashim, Jerusalem, IL;

Inventor:

Uriel Heresco-Levy, Jerusalem, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/198 (2006.01); A61K 45/06 (2006.01); A61K 31/496 (2006.01);
U.S. Cl.
CPC ...
A61K 31/198 (2013.01); A61K 31/496 (2013.01); A61K 45/06 (2013.01);
Abstract

This invention provides a method of enhancing NMDAR-mediated neurotransmission in a disease associated with NMDAR antibody production, said method comprising administering an NMDAR agonist, an alanine-serine-cysteine transporter inhibitor, a D-amino acid oxidase inhibitor, a glycine transport inhibitor or a combination thereof to said subject. This invention also provides a method of mitigating the severity of, mitigating the pathogenesis of, lowering the incidence of or treating a disease associated with NMDAR antibody production, said method comprising administering an agent, which is an NMDAR agonist, an alanine-serine-cysteine transporter inhibitor, a D-amino acid oxidase inhibitor, a glycine transport inhibitor or a combination thereof to said subject.


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