The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 20, 2017

Filed:

May. 11, 2015
Applicant:

Cellomics, Inc., Pittsburgh, PA (US);

Inventors:

Richik Niloy Ghosh, Upper St. Clair, PA (US);

Dirk John VandenBerg, III, Pittsburgh, PA (US);

Keith Rao Heffley, Pittsburgh, PA (US);

Monica Jo Tomaszewski, Pittsburgh, PA (US);

Jeffrey Robert Haskins, Mars, PA (US);

Assignee:

CELLOMICS, INC., Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/25 (2006.01); G01N 21/64 (2006.01); G02B 5/02 (2006.01); G01N 33/487 (2006.01); F21Y 105/00 (2016.01);
U.S. Cl.
CPC ...
G01N 21/6486 (2013.01); G01N 21/253 (2013.01); G01N 21/6452 (2013.01); G01N 21/6458 (2013.01); G01N 33/487 (2013.01); G02B 5/0278 (2013.01); G02B 5/0294 (2013.01); F21Y 2105/003 (2013.01); G01N 21/255 (2013.01); G01N 2021/6491 (2013.01); G01N 2201/0627 (2013.01);
Abstract

A system and method that images biological samples and uses chromophores to analyze the imaged samples. The chromophore analysis can be done by itself or in conjunction with fluorophore analysis in High Content Imaging systems. To perform chromophore analysis the biological samples can be labeled with different chromophores and imaged using transmitted light that is at least partially absorbed by the chromophores. To also perform fluorophore analysis the samples can also be labeled with fluorophores that are excited by excitation light. The chromophore analysis and fluorophore analysis can be performed separately or concurrently using a High Content Imaging system. The system provides the expanded capability by illuminating the chromophore-labeled samples with transmitted light of different wavelengths and automatically detecting the images which represent the differential absorption of the colored lights by the sample.


Find Patent Forward Citations

Loading…