The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 20, 2017

Filed:

Jun. 30, 2015
Applicant:

Gnubio, Inc., Cambridge, MA (US);

Inventors:

Christopher Possinger, Cambridge, MA (US);

Sepehr Kiani, Cambridge, MA (US);

Assignee:

Bio-Rad Laboratories, Inc., Hercules, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/00 (2006.01); C12Q 1/68 (2006.01); C12P 19/34 (2006.01); C07H 21/02 (2006.01); G01N 25/00 (2006.01); F28F 13/14 (2006.01); B01L 7/00 (2006.01); F25B 21/04 (2006.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
F28F 13/14 (2013.01); B01L 7/525 (2013.01); C12P 19/34 (2013.01); B01L 3/502784 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0883 (2013.01); B01L 2300/1805 (2013.01); B01L 2300/1822 (2013.01); B01L 2300/1883 (2013.01); F25B 21/04 (2013.01); F28F 2270/00 (2013.01); F28F 2275/20 (2013.01);
Abstract

The present invention generally pertains to a system which utilizes floating thermal contact to enable PCR, in a thermal management device. Comprised of multiple thermal zones attached to a framework, each zone an individually actuated, isolated sub-assembly. The actuation of each zone ensures physical contact with an uneven, yet flat microfluidic chip to achieve effective, conductive heat transfer. The isolation of each zone serves to insulate the thermal zones from each other and minimize undesired heat transfer between adjacent zones, so that each zone is at a proper, uniform temperature.


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