The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 20, 2017

Filed:

Sep. 19, 2013
Applicants:

Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);

Washington University, St. Louis, MI (US);

Inventors:

Dan Barouch, Newton, MA (US);

Herbert W Virgin, Saint Louis, MO (US);

David Wang, Saint Louis, MO (US);

Guoyan Zhao, Saint Louis, MO (US);

Larissa Thackray, Columbia, IL (US);

Scott Handley, Saint Louis, MO (US);

Rachel Presti, University City, MO (US);

Assignees:

Beth Israel Deaconess, Boston, MA (US);

Washington University, Saint Louis, MO (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/70 (2006.01); A61K 39/235 (2006.01); A61K 39/21 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/703 (2013.01); C12N 7/00 (2013.01); A61K 39/00 (2013.01); C12N 2710/10321 (2013.01); C12N 2710/20021 (2013.01); C12N 2710/22021 (2013.01); C12N 2720/00021 (2013.01); C12N 2750/14021 (2013.01); C12N 2750/14121 (2013.01); C12N 2770/16021 (2013.01); C12N 2770/32021 (2013.01); C12N 2770/32321 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/158 (2013.01);
Abstract

The present invention relates to previously undescribed viruses that are associated with significant expansion of the virome, immunodeficiency, and enteropathy during lentiviral infection. The invention also provides methods to detect acquired immune deficiency syndrome (AIDS) or AIDS progression in a subject, methods to diagnose immunodeficiency or enteropathy in a subject, and methods to identify a therapeutic agent to treat the same.


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