The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 20, 2017
Filed:
Apr. 05, 2010
Applicants:
Meng Wang, Norwich, GB;
Zizhen Yang, London, GB;
Cristina Rada, Cambridge, GB;
Michael Neuberger, Cambridge, GB;
Inventors:
Meng Wang, Norwich, GB;
Zizhen Yang, London, GB;
Cristina Rada, Cambridge, GB;
Michael Neuberger, Cambridge, GB;
Assignee:
Medical Research Council, Wiltshire, GB;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/78 (2006.01); C12N 15/00 (2006.01); C12N 15/85 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/78 (2013.01); C07K 16/00 (2013.01); C12Y 305/04005 (2013.01); C07K 2319/23 (2013.01); C12N 2799/027 (2013.01);
Abstract
The invention provides functional mutants of activation-induced cytidine deaminase (AID) protein that have increased activity as compared to a wild-type AID protein. The invention also provides nucleic acids encoding the functional AID mutants, and vectors and cells comprising the nucleic acids. The invention further provides methods of using the functional mutant AID proteins.