The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9683222 B1

PDF
Full Text
Expired
Date of Patent:
Jun. 20, 2017

Filed:

May. 19, 2015
Applicant:

Ligacept, Llc, Oak Brook, IL (US);

Inventor:

Jason Hill, Chicago, IL (US);

Assignee:

Ligacept LLC, Oak Brook, IL (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/71 (2006.01); C07K 19/00 (2006.01); A61K 38/17 (2006.01); C12N 9/12 (2006.01); C07K 14/475 (2006.01); C07K 14/705 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/12 (2013.01); C07K 14/475 (2013.01); A61K 38/00 (2013.01); A61K 38/177 (2013.01); A61K 38/179 (2013.01); C07K 14/705 (2013.01); C07K 14/71 (2013.01); C07K 2319/30 (2013.01); C07K 2319/32 (2013.01); C12Y 207/10001 (2013.01);
Abstract

Chimeric ErbB ligand binding molecules having detectable binding activity for more ErbB ligands than any one of native ErbB1, ErbB3 or ErbB4 are disclosed. Preferably, the binding molecules bind a broad spectrum and, more preferably, the full spectrum of ErbB ligands. The chimeric ErbB ligand binding molecules generally have a subunit LI derived from one of Erb-B1, 3, or 4 and a subunit LII derived from another distinct ErbB receptor type. The sub-domain, SI, which joins LI and LII can be from either one of the receptor types or can have portions from both. Pharmaceutical compositions that contain the molecules and methods for the treatment of ErbB sensitive diseases are also disclosed.


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Hill, Jason. (2017). Broad spectrum erbb ligand binding molecules and methods for preparing and using them (U.S. Patent No. 9683222). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9683222

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