The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 20, 2017
Filed:
Oct. 29, 2013
Applicant:
Cancer Research Technology Limited, London, Greater London, GB;
Inventors:
Jorg Klingelhöfer, Copenhagen, DK;
Noona Ambartsumian, Copenhagen, DK;
Mariam Grigorian, Copenhagen, DK;
Eugene Lukanidin, Copenhagen, DK;
Assignee:
Cancer Research Technology Limited, London, GB;
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); C07K 16/30 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); G01N 33/574 (2006.01); A61K 39/00 (2006.01); A61N 5/10 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 39/39558 (2013.01); A61K 45/06 (2013.01); C07K 16/30 (2013.01); G01N 33/57415 (2013.01); A61K 2039/505 (2013.01); A61N 2005/1098 (2013.01); C07K 2317/24 (2013.01); C07K 2317/30 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); G01N 2333/4727 (2013.01);
Abstract
Anti-S100A4 antibody molecules that are capable of inhibiting the biological activity of S100A4 in promoting tumor progression and/or in inducing tumor metastasis are described. The antibody molecules are also useful in the treatment of inflammatory conditions. The properties of the antibodies are demonstrated using in vitro and in vivo assays.