The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 20, 2017

Filed:

Mar. 13, 2014
Applicant:

Janssen Pharmaceutica NV, Beerse, BE;

Inventors:

Wenying Chai, San Diego, CA (US);

Charlotte Deckhut, San Diego, CA (US);

Curt A. Dvorak, Poway, CA (US);

Wendy Eccles, San Diego, CA (US);

James P. Edwards, San Diego, CA (US);

Steven D. Goldberg, Encinitas, CA (US);

Paul J. Krawczuk, San Diego, CA (US);

Alec D. Lebsack, Ladera Ranch, CA (US);

Jing Liu, San Diego, CA (US);

Virginia M. Tanis, Carlsbad, CA (US);

Kyle T. Tarantino, Princeton, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 417/14 (2006.01); C07D 401/12 (2006.01); C07D 413/14 (2006.01); C07D 401/14 (2006.01); C07D 417/12 (2006.01); C07D 405/14 (2006.01); A61K 31/428 (2006.01); A61K 31/4709 (2006.01); A61K 31/4725 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); A61K 31/428 (2013.01); A61K 31/4709 (2013.01); A61K 31/4725 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01);
Abstract

The present invention relates to compounds of Formula (I), and solvates, hydrates, and pharmaceutically acceptable salts thereof, wherein ring A, R, Rand Rare as defined herein, useful as FLAP modulators. The invention also relates to pharmaceutical compositions comprising compounds of Formula (I). Methods of making and using the compounds of Formula (I) are also within the scope of the invention.


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