The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9682961 B1

PDF
Full Text
Expired
Date of Patent:
Jun. 20, 2017

Filed:

Dec. 05, 2014
Applicants:

Carna Biosciences, Inc., Kobe-shi, Hyogo, JP;

National Cancer Center, Tokyo, JP;

Inventors:

Hideki Moriyama, Kobe, JP;

Masaaki Sawa, Ibaraki, JP;

Yuko Uno, Kobe, JP;

Shigeki Kashimoto, Osaka, JP;

Tesshi Yamada, Tokyo, JP;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); C07D 401/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01);
Abstract

The present invention provides a quinazoline derivative represented by the following formula (I): wherein Rand Rrepresent a hydrogen atom, a halogen atom, or a lower alkyl group optionally having a substituent; Z represents a cycloalkyl group having a substituent or a cycloalkenyl group having a substituent; and Q represents a bicyclic heteroaryl group optionally having a substituent, or a pharmaceutically acceptable salt thereof. Since the compound has an inhibitory effect on the Wnt/β-catenin signaling pathway and exhibits an antitumor effect, it is useful as a medicine.


Find Patent Forward Citations

Moriyama, Hideki. (2017). Quinazoline derivative (U.S. Patent No. 9682961). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9682961

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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