The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 20, 2017
Filed:
Dec. 05, 2014
Carna Biosciences, Inc., Kobe-shi, Hyogo, JP;
National Cancer Center, Tokyo, JP;
Hideki Moriyama, Kobe, JP;
Masaaki Sawa, Ibaraki, JP;
Yuko Uno, Kobe, JP;
Shigeki Kashimoto, Osaka, JP;
Tesshi Yamada, Tokyo, JP;
CARNA BIOSCIENCES, INC., Kobe-Shi, JP;
NATIONAL CANCER CENTER, Tokyo, JP;
Abstract
The present invention provides a quinazoline derivative represented by the following formula (I): wherein Rand Rrepresent a hydrogen atom, a halogen atom, or a lower alkyl group optionally having a substituent; Z represents a cycloalkyl group having a substituent or a cycloalkenyl group having a substituent; and Q represents a bicyclic heteroaryl group optionally having a substituent, or a pharmaceutically acceptable salt thereof. Since the compound has an inhibitory effect on the Wnt/β-catenin signaling pathway and exhibits an antitumor effect, it is useful as a medicine.