The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 20, 2017

Filed:

Aug. 07, 2013
Applicant:

Jw Creagene Inc., Seongnam-si, KR;

Inventors:

Yong Soo Bae, Suwon-si, KR;

Seung Ho Hong, Seongnam-si, KR;

Young Hoon Kim, Namyangju-si, KR;

Seung Soo Han, Seongnam-si, KR;

Jin Kim, Seoul, KR;

Assignee:

JW CREAGENE INC., Seongnam-si, KR;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/21 (2006.01); A61K 39/00 (2006.01); A61K 38/03 (2006.01); C07K 14/56 (2006.01); C12P 7/20 (2006.01); A61K 47/48 (2006.01); A61K 38/16 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48215 (2013.01); A61K 38/16 (2013.01); A61K 38/212 (2013.01); C07K 14/56 (2013.01); C07K 2319/00 (2013.01); C07K 2319/10 (2013.01);
Abstract

The present invention relates to IFN-α fusion protein in which a cytoplasmic transduction peptide (CTP) and polyethylene glycol (PEG) are bonded to an IFN-α protein. The IFN-α fusion protein of the present invention is characterized in that the specific activity of interferon remains high, the half-life of the INF-α fusion protein is extended when delivered in vivo, and the mobility of the interferon in a liver is improved. The IFN-α fusion protein of the present invention can be used in the development of protein drugs effective in preventing or treating liver diseases, including various types of viral infections or the like.


Find Patent Forward Citations

Loading…