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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9682085 B1

PDFFull Text
Expired
Date of Patent:
Jun. 20, 2017

Filed:

Mar. 11, 2014

Anti-proprotein convertase subtilisin kexin type 9 (anti-pcsk9) compounds and methods of using the same in the treatment and/or prevention of cardiovascular diseases

Applicant:

Shifa Biomedical Corporation, Malvern, PA (US);

Inventors:

Sherin Salaheldin Abdel-Meguid, Exton, PA (US);

Nabil Elshourbagy, Chester, PA (US);

Harold Meyers, Weston, PA (US);

Shaker A. Mousa, Wynantskill, NY (US);

Assignee:

Shifa Biomedical Corporation, Malvern, PA (US);

Attorneys:

Patrick J. Hagan

Dann, Dorfman, Herrell and Skillman

Primary Examiner:

Samira Jean-Louis

Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/4015 (2006.01); A61K 31/4439 (2006.01); A61K 31/433 (2006.01); A61K 31/42 (2006.01); A61K 31/4196 (2006.01); A61K 31/426 (2006.01); A61K 31/404 (2006.01); A61K 31/4155 (2006.01); A61K 31/415 (2006.01); A61K 31/4545 (2006.01); A61K 31/4178 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61K 31/404 (2013.01); A61K 31/415 (2013.01); A61K 31/4155 (2013.01); A61K 31/4178 (2013.01); A61K 31/4196 (2013.01); A61K 31/42 (2013.01); A61K 31/426 (2013.01); A61K 31/433 (2013.01); A61K 31/4439 (2013.01); A61K 31/4545 (2013.01); A61K 31/4015 (2013.01);
Abstract

Disclosed are compounds that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), as well as therapeutic methods for use of such compounds to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease (CVD), including treatment of hypercholesterolemia. Examples of compounds include thiadiazole, isoxazole, 1,2,4-triazole, thiazole, indole, pyrazole, and pyrrolinone derivatives.

Find Patent Forward Citations

Abdel-Meguid, Sherin. (2017). Anti-proprotein convertase subtilisin kexin type 9 (anti-pcsk9) compounds and methods of using the same in the treatment and/or prevention of cardiovascular diseases (U.S. Patent No. 9682085). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9682085

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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