The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 20, 2017

Filed:

Mar. 30, 2012
Applicants:

Brian Lee, South San Franciso, CA (US);

Kui Lin, South San Francisco, CA (US);

Michelle Nannini, South San Francisco, CA (US);

Elizabeth Punnoose, South San Francisco, CA (US);

Deepak Sampath, South San Francisco, CA (US);

Inventors:

Brian Lee, South San Franciso, CA (US);

Kui Lin, South San Francisco, CA (US);

Michelle Nannini, South San Francisco, CA (US);

Elizabeth Punnoose, South San Francisco, CA (US);

Deepak Sampath, South San Francisco, CA (US);

Assignee:

GENENTECH, INC., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); A61K 31/165 (2006.01); A61K 31/4402 (2006.01); A61K 45/06 (2006.01); C07D 239/70 (2006.01); A61K 31/166 (2006.01); A61K 31/4523 (2006.01);
U.S. Cl.
CPC ...
A61K 31/517 (2013.01); A61K 31/165 (2013.01); A61K 31/166 (2013.01); A61K 31/4402 (2013.01); A61K 31/4523 (2013.01); A61K 45/06 (2013.01); C07D 239/70 (2013.01);
Abstract

The invention provides combinations comprising a) compound of formula I: (formula I), or a pharmaceutically acceptable salt thereof; and another agent selected from GDC-0973, PD-0325901, or a pharmaceutically acceptable salt thereof. The combinations are particularly useful for treating hyperproliferative disorders, such as cancer.


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