The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 20, 2017

Filed:

May. 25, 2016
Applicant:

Nusirt Sciences, Inc., Nashville, TN (US);

Inventors:

Michael Zemel, Knoxville, TN (US);

E. Douglas Grindstaff, II, Nashville, TN (US);

Antje Bruckbauer, Knoxville, TN (US);

Assignee:

NuSirt Sciences, Inc., Nashville, TN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/198 (2006.01); A61K 31/336 (2006.01); A61K 31/366 (2006.01); A61K 31/522 (2006.01); A61K 31/191 (2006.01); A61K 31/216 (2006.01); A61K 38/22 (2006.01); A23L 2/52 (2006.01); A61K 31/194 (2006.01); A61K 31/4439 (2006.01); A61K 31/19 (2006.01); A61K 45/06 (2006.01); A61K 36/87 (2006.01); A61K 31/05 (2006.01); A61K 31/192 (2006.01); A61K 31/353 (2006.01); A61K 31/015 (2006.01); A61K 31/155 (2006.01); A61K 31/426 (2006.01); A23L 33/00 (2016.01); A23L 33/175 (2016.01);
U.S. Cl.
CPC ...
A61K 31/198 (2013.01); A23L 2/52 (2013.01); A23L 33/175 (2016.08); A23L 33/30 (2016.08); A61K 31/015 (2013.01); A61K 31/05 (2013.01); A61K 31/155 (2013.01); A61K 31/19 (2013.01); A61K 31/191 (2013.01); A61K 31/192 (2013.01); A61K 31/194 (2013.01); A61K 31/216 (2013.01); A61K 31/336 (2013.01); A61K 31/353 (2013.01); A61K 31/366 (2013.01); A61K 31/426 (2013.01); A61K 31/4439 (2013.01); A61K 31/522 (2013.01); A61K 36/87 (2013.01); A61K 38/22 (2013.01); A61K 45/06 (2013.01); A23V 2002/00 (2013.01);
Abstract

Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.


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