The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 20, 2017

Filed:

May. 02, 2014
Applicant:

Signpath Pharma Inc., Quakertown, PA (US);

Inventor:

Lawrence Helson, Quakertown, PA (US);

Assignee:

SignPath Pharma Inc., Quakertown, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); A61K 31/12 (2006.01); A61K 31/445 (2006.01); A61K 31/4545 (2006.01);
U.S. Cl.
CPC ...
A61K 9/127 (2013.01); A61K 31/12 (2013.01); A61K 31/445 (2013.01); A61K 31/4545 (2013.01);
Abstract

Compositions and methods for the treatment of drug-induced long QT syndrome and other cardiac channelopathies are disclosed herein. The compositions and methods of the present invention comprise binding one or more QT prolonging drugs with a liposome prior to parenteral (intravenous or subcutaneous) administration, or administration of an empty liposome prior to or concomitantly with therapeutic agents known to have a high risk of QT prolongation, or immediately following an envenomation. The results presented show an abrogation of the adverse effects of QT prolonging drugs in a dose-dependent manner by the compositions of the present invention.


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