The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 13, 2017

Filed:

Feb. 10, 2012
Applicants:

Jiaming YE, Beijing, CN;

Pinhong Wang, Beijing, CN;

Guoqing Wang, Beijing, CN;

Liqing Duan, Beijing, CN;

Kaijun Zhao, Beijing, CN;

Jinxiu Zhang, Beijing, CN;

Xiumei Song, Beijing, CN;

Dong Wang, Beijing, CN;

Huafang Gao, Beijing, CN;

Wanli Xing, Beijing, CN;

Inventors:

Jiaming Ye, Beijing, CN;

Pinhong Wang, Beijing, CN;

Guoqing Wang, Beijing, CN;

Liqing Duan, Beijing, CN;

Kaijun Zhao, Beijing, CN;

Jinxiu Zhang, Beijing, CN;

Xiumei Song, Beijing, CN;

Dong Wang, Beijing, CN;

Huafang Gao, Beijing, CN;

Wanli Xing, Beijing, CN;

Assignees:

CAPITALBIO CORPORATION, Beijing, CN;

TSINGHUA UNIVERSITY, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 33/50 (2006.01); G01N 33/543 (2006.01); B01L 3/00 (2006.01); B01L 7/00 (2006.01); G01N 35/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6876 (2013.01); B01L 3/5027 (2013.01); B01L 7/52 (2013.01); B01L 2300/0636 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0887 (2013.01); B01L 2300/1822 (2013.01); B01L 2300/1827 (2013.01); B01L 2300/1844 (2013.01); B01L 2400/0622 (2013.01); G01N 33/543 (2013.01); G01N 2035/00158 (2013.01);
Abstract

A hybridization system is provided, which comprises a biological chip having a substrate () with a probe dot matrix () and a cover plate () with at least two through-holes (), where a hybrid chamber () is formed between the substrate () and the cover plate (), at least two fluid channels () are interconnected respectively with the hybrid chamber () by the two through-holes (), and a fluid control device is interconnected with the fluid channels (). The biological chip hybridization system integrates hybridizing, cleaning and drying functions, uses power provided by the fluid control device as the drive force for promoting the liquid flow for automatically reciprocation flow in the fluid channels () and the chamber () to achieve a dynamic hybridization, thus improving the hybrid efficiency and uniformity, and achieving automatic control.


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