The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 13, 2017
Filed:
Jan. 11, 2011
Kent E. S. Matlack, San Francisco, CA (US);
Susan L. Lindquist, Cambridge, MA (US);
Sebastian Treusch, San Francisco, CA (US);
Kent E. S. Matlack, San Francisco, CA (US);
Susan L. Lindquist, Cambridge, MA (US);
Sebastian Treusch, San Francisco, CA (US);
Whitehead Insititute for Biomedical Research, Cambridge, MA (US);
Abstract
Disclosed are yeast cells expressing a polypeptide comprising a signal sequence and a human amyloid beta protein. Also disclosed are methods of screening yeast cells to identify compounds that prevent or suppress amyloid beta-induced toxicity and genetic suppressors or enhancers of amyloid beta-induced toxicity. Compounds identified by such screens can be used to treat or prevent neurodegenerative disorders such as Alzheimer's disease.