The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 13, 2017

Filed:

Sep. 23, 2014
Applicant:

Apim Therapeutics As, Trondheim, NO;

Inventors:

Marit Otterlei, Trondheim, NO;

Per Arne Aas, Trondheim, NO;

Emadoldin Feyzi, Trondheim, NO;

Assignee:

APIM THERAPEUTICS AS, Trondheim, NO;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/08 (2006.01); A61K 38/16 (2006.01); C07K 7/04 (2006.01); C07K 9/00 (2006.01); C07K 14/00 (2006.01); C07K 14/47 (2006.01); G01N 33/68 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/00 (2013.01); C07K 14/4738 (2013.01); G01N 33/6872 (2013.01); G01N 33/6893 (2013.01); A61K 38/00 (2013.01); C07K 2319/10 (2013.01); G01N 2800/56 (2013.01);
Abstract

Disclosed is an oligopeptidic compound capable of interacting with proliferating cell nuclear antigen (PCNA), wherein the compound comprises a PCNA interacting motif which is: wherein the oligopeptidic compound has 9-70 subunits and comprises at least one signal sequence, wherein the signal sequence is a nuclear localization signal sequence and/or a cell penetrating signal sequence and wherein in said compound a PCNA interacting motif is N-terminal to a signal sequence. Also disclosed are methods of treatment of a disorder or condition where it is desirable to inhibit the growth of cells, or a method of treatment which involves cytostatic therapy, or a method of treatment of inflammation said method comprising administering the oligopeptidic compound to a subject in need thereof.


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