The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 13, 2017
Filed:
Jan. 17, 2014
Applicant:
University of Kansas, Lawrence, KS (US);
Inventors:
Deepak B. Salunke, Lawrence, KS (US);
Xiaoqiang Guo, Lawrence, KS (US);
Sunil A. David, Lawerence, KS (US);
Assignee:
University of Kansas, Lawrence, KS (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 5/068 (2006.01); A61K 39/39 (2006.01); C07K 14/705 (2006.01); C07K 5/062 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 5/06086 (2013.01); A61K 39/39 (2013.01); C07K 5/0606 (2013.01); C07K 14/705 (2013.01); A61K 38/00 (2013.01); A61K 2039/55516 (2013.01);
Abstract
The present disclosure is directed to a novel class of toll-like receptor 2-agonistic (TLR2) lipopeptide compounds having specific structures, and synthetic methods of making the compounds. These compounds provide high potency of agonistic activities with human, other than murine, TLR2, and are useful as vaccine adjuvants. Vaccines are perhaps one of the most successful medical interventions against infectious disease.