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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9676793 B1

PDFFull Text
Expired
Date of Patent:
Jun. 13, 2017

Filed:

Dec. 21, 2015

Co-crystals of 5-amino-2-oxothiazolo[4,5-d]pyrimidin-3(2h)-yl-5-hydroxymethyl tetrahydrofuran-3-yl acetate and methods for preparing and using the same

Applicant:

Hoffmann-la Roche Inc., Little Falls, NJ (US);

Inventors:

Urs Schwitter, Basel, CH;

Fritz Bliss, Basel, CH;

Michael Kammerer, Basel, CH;

Florence Tixeront, Basel, CH;

Assignee:

Hoffmann-LaRoche Inc., Little Falls, NJ (US);

Attorney:

Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.

Primary Examiner:

Kahsay Habte

Int. Cl.
CPC ...
C07D 513/04 (2006.01); C07C 55/12 (2006.01); C07C 55/08 (2006.01); C07C 57/15 (2006.01); C07C 55/14 (2006.01); C07C 59/06 (2006.01); C07C 59/185 (2006.01);
U.S. Cl.
CPC ...
C07D 513/04 (2013.01); C07C 55/08 (2013.01); C07C 55/12 (2013.01); C07C 55/14 (2013.01); C07C 57/15 (2013.01); C07C 59/06 (2013.01); C07C 59/185 (2013.01);
Abstract

Co-crystals of Formula I compounds and their pharmaceutical compositions are novel therapeutics for the treatment of diseases, such as human immunodeficiency virus (HIV) infection, hepatitis B virus (HBV) infection, hepatitis C virus (HCV) infection and cancer. The co-crystal are more stable to oxidation and aqueous degradation, have a better pharmacokinetic profile and superior biological activity than the corresponding tosylate salt form of Formula I compound.

Find Patent Forward Citations

Schwitter, Urs. (2017). Co-crystals of 5-amino-2-oxothiazolo[4,5-d]pyrimidin-3(2h)-yl-5-hydroxymethyl tetrahydrofuran-3-yl acetate and methods for preparing and using the same (U.S. Patent No. 9676793). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9676793

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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