The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 13, 2017

Filed:

Feb. 05, 2015
Applicants:

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Washington, DC (US);

University of Hawaii, Honolulu, HI (US);

Inventors:

William J. Chain, Honolulu, HI (US);

John A. Beutler, Union Bridge, MD (US);

David Fash, Honolulu, HI (US);

William D. Figg, Fairfax, VA (US);

Zhenwu Li, West Haven, CT (US);

Cody John Peer, Frederick, MD (US);

Joe William Ramos, Honolulu, HI (US);

Florian J. Sulzmaier, San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 493/08 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01); A61K 31/352 (2006.01);
U.S. Cl.
CPC ...
C07D 493/08 (2013.01); A61K 9/0053 (2013.01); A61K 31/352 (2013.01); A61K 45/06 (2013.01);
Abstract

Disclosed is a compound of formula (I) or formula (II): (Formulas should be inserted here) wherein R-Rare as defined herein. Also disclosed are a pharmaceutical composition comprising such a compound and a method of treating or preventing cancer in a mammal in need thereof, comprising administering to the mammal a compound of formula (I) or formula (II).


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