The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 13, 2017
Filed:
Dec. 20, 2013
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Amjad Ali, Rahway, NJ (US);
Michael Man-chu Lo, Rahway, NJ (US);
Yeon-hee Lim, Rahway, NJ (US);
Andrew Stamford, Rahway, NJ (US);
Rongze Kuang, Rahway, NJ (US);
Paul Tempest, Shanghai, CN;
Younong Yu, Rahway, NJ (US);
Michael Berlin, Flemington, NJ (US);
Pauline Ting, Rahway, NJ (US);
Gang Zhou, Rahway, NJ (US);
Tao Yu, Rahway, NJ (US);
Christopher Boyce, Rahway, NJ (US);
Joseph Michael Kelly, Rahway, NJ (US);
Jayaram R. Tagat, Kenilworth, NJ (US);
Junying Zheng, Rahway, NJ (US);
Xianhai Huang, Rahway, NJ (US);
Wei Zhou, Rahway, NJ (US);
Jae-hun Kim, Rahway, NJ (US);
Nicolas Zorn, Rahway, FR;
Dong Xiao, Kenilworth, NJ (US);
Gioconda V. Gallo, Rahway, NJ (US);
Walter Won, Rahway, NJ (US);
Heping Wu, Rahway, NJ (US);
Rajan Anand, Rahway, NJ (US);
Qiaolin Deng, Rahway, NJ (US);
Amjad Ali, Freehold, NJ (US);
Michael Man-Chu Lo, Bedminister, NJ (US);
Yeon-Hee Lim, Piscataway, NJ (US);
Andrew Stamford, Chatham, NJ (US);
Rongze Kuang, Green Brook, NJ (US);
Paul Tempest, Shanghai, CN;
Younong Yu, East Brunswick, NJ (US);
Michael Berlin, Flemington, NJ (US);
Pauline Ting, New Providence, NJ (US);
Gang Zhou, Bridgewater, NJ (US);
Tao Yu, Edison, NJ (US);
Christopher Boyce, Flemington, NJ (US);
Joseph Michael Kelly, Parlin, NJ (US);
Jayaram R. Tagat, Westfield, NJ (US);
Junying Zheng, New Providence, NJ (US);
Xianhai Huang, Warren, NJ (US);
Wei Zhou, Scotch Plains, NJ (US);
Jae-Hun Kim, Scotch Plains, NJ (US);
Nicolas Zorn, Durmenach, FR;
Dong Xiao, Warren, NJ (US);
Gioconda V. Gallo, Summit, NJ (US);
Walter Won, Alpine, NJ (US);
Heping Wu, Edison, NJ (US);
Rajan Anand, Fanwood, NJ (US);
Qiaolin Deng, Edison, NJ (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
Disclosed are compounds of Formula A: (structurally represented) where 'RG1', 'RG2a', “RG4”, “RG5”, “MG1”, “n” and “m” are defined herein which compounds are antagonists of A2A receptor. Disclosed herein also are uses of the compounds described herein as antagonists of the A2a receptor in the potential treatment or prevention of neurological disorders and diseases in which A2A receptors are involved. Disclosed herein also are pharmaceutical compositions comprising these compounds and uses of these pharmaceutical compositions.