The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 13, 2017
Filed:
Jul. 25, 2013
Centre National DE LA Recherche Scientifique, Paris, FR;
Universite DE Montpellier, Montpellier, FR;
Uniwersytet Jagiellonski, Cracow, PL;
Instytut Farmakologii Polskiej Akademii Nauk, Cracow, PL;
Pawel Zajdel, Kraków, PL;
Katarzyna Grychowska, Kraków, PL;
Maciej Pawlowski, Wieliczka, PL;
Anna Partyka, Kraków, PL;
Anna Wesolowska, Kraków, PL;
Andrzej J. Bojarski, Zabierzów, PL;
Piotr Popik, Kraków, PL;
Tomasz Kos, Kraków, PL;
Grzegorz Satala, Kraków, PL;
Frederic Lamaty, Montpellier, FR;
Evelina Colacino, Montpellier, FR;
Jean Martinez, Caux, FR;
Gilles Subra, Saint Gély du Fesc, FR;
Xavier Bantreil, Aigues-vives, FR;
Uniwersyter Jagiellonski, Cracow, PL;
Instytut Farmakologii Polskiej Akademii Nauk, Cracow, PL;
Centre National De La Recherche Scientifique, Paris, FR;
Universite de Montpellier, Montpellier, FR;
Abstract
This invention concerns pyrroloquinoline derivatives as antagonists of 5-HT6 receptors, to methods for the preparation of these compounds and to novel intermediates useful for their synthesis. The invention also relates to the uses of such compounds and compositions, particularly their use in administering them to patients to achieve a therapeutic effect in schizophrenia, anxiety, depression, maniac depression, epilepsy, obsessive compulsive disorders, mood disorders, migraine, Alzheimer's disease, age related cognitive decline, mild cognitive impairment, sleep disorders, eating disorders, anorexia, bulimia, panic attacks, attention deficit hyperactivity disorder, attention deficit disorder, Parkinson's disease, Huntington's disease, withdrawal from abuse of cocaine, ethanol, nicotine or benzodiazepines, pain, obesity and type-2 diabetes, functional bowel disorder, Irritable Bowel Syndrome. The compounds have the general formula (XIV), wherein the symbols have the meanings given in the description.