The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 13, 2017
Filed:
Mar. 25, 2014
Ono Pharmaceutical Co., Ltd., Osaka, JP;
Kensuke Kusumi, Osaka, JP;
Atsushi Naganawa, Osaka, JP;
Kazuhiro Otsuki, Osaka, JP;
Tetsuya Sekiguchi, Osaka, JP;
Koji Shinozaki, Osaka, JP;
Hiroshi Yamamoto, Osaka, JP;
Yasuko Yamamoto, Osaka, JP;
ONO PHARMACEUTICAL CO., LTD., Osaka, JP;
Abstract
An object of the present invention is to provide a compound having strong human S1Pantagonistic activity in order to develop a useful medicament for therapy of a S1P-mediated disease such as a disease resulting from vascular constriction, fibrosis and respiratory disease. The compound represented by the general formula (I), wherein all the symbols have the same meanings as described in the specification, has a halogen atom or a haloalkyl group and a phenoxy group at certain substitution sites, and thus has strong human S1Pantagonistic activity. Therefore, the compound can be a therapeutic agent for a S1P-mediated disease, such as a disease resulting from vascular constriction, fibrosis and respiratory disease.