The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 13, 2017

Filed:

Mar. 14, 2014
Applicants:

Cayman Chemical Company, Inc., Ann Arbor, MI (US);

Myometrics, Llc, New London, CT (US);

Inventors:

Stephen Douglas Barrett, Hartland, MI (US);

Bradlee David Germain, Ann Arbor, MI (US);

Adam Uzieblo, Farmington Hills, MI (US);

Fred Lawrence Ciske, Dexter, MI (US);

Gregory William Endres, Saline, MI (US);

Andriy Kornilov, Ypsilanti, MI (US);

Kirk M. Maxey, Ann Arbor, MI (US);

James Paul O'Malley, Dunedin, NZ;

Thomas Allen Owen, Pompton Plains, NJ (US);

Assignee:

CAYMAN CHEMICAL COMPANY, INC., Ann Arbor, MI (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 207/27 (2006.01); C07D 417/06 (2006.01); C07D 207/12 (2006.01); C07D 409/06 (2006.01);
U.S. Cl.
CPC ...
C07D 207/27 (2013.01); C07D 207/12 (2013.01); C07D 409/06 (2013.01); C07D 417/06 (2013.01);
Abstract

Disclosed herein are compounds of formula (I) wherein L, L, L, R, R, R, and Rare as defined in the specification. Compounds of formula (I) are EPagonists useful in the treatment of glaucoma, osteoporosis, bone fracture, periodontal bone loss, orthopedic implant, alopecia, neuropathic pain, and related disorders. Pharmaceutical compositions and methods of treating conditions or disorders are also described.


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