The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 13, 2017
Filed:
Aug. 08, 2014
Santen Pharmaceutical Co., Ltd., Osaka-shi, Osaka, JP;
Kazuhiro Kudou, Ikoma, JP;
Masato Nagatsuka, Ikoma, JP;
SANTEN PHARMACEUTICAL CO., LTD., Osaka, JP;
Abstract
An object is to provide a novel production method suitable for industrial production of a 3,3-dimethyl-3,4-dihydro-1H-quinoxalin-2-one derivative and a synthetic intermediate for the method. Provided is a method for producing a compound represented by formula (1): wherein Rrepresents a hydrogen atom, an optionally substituted alkyl group, an optionally substituted cycloalkyl group, or an optionally substituted aryl group, Rrepresents a hydrogen atom, an optionally substituted alkyl group, a hydroxy group, or nitrogen atom-protecting group, Rrepresents a hydrogen atom, an optionally substituted alkyl group, a hydroxy group, or a nitrogen atom-protecting group, and X represents a hydroxy group or a leaving group,or a salt thereof, the method comprising the steps of: wherein R, R, and X are the same as defined in formula (1), Rrepresents an optionally substituted alkyl group, an optionally substituted cycloalkyl group, or an optionally substituted aryl group, wherein R, R, R, and X are the same as defined in formulae (1) and (2),or a salt thereof, and