The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 13, 2017

Filed:

Nov. 03, 2015
Applicant:

The Florida State University Research Foundation, Inc., Tallahassee, FL (US);

Inventors:

Igor V. Alabugin, Tallahassee, FL (US);

Kamalkishore Pati, Tallahassee, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 7/22 (2006.01); C07C 1/32 (2006.01); C07D 221/18 (2006.01); C07D 317/70 (2006.01); C07C 41/18 (2006.01); C07C 45/67 (2006.01); C07C 253/30 (2006.01); C07C 17/26 (2006.01);
U.S. Cl.
CPC ...
C07C 1/325 (2013.01); C07C 17/26 (2013.01); C07C 41/18 (2013.01); C07C 45/67 (2013.01); C07C 253/30 (2013.01); C07D 221/18 (2013.01); C07D 317/70 (2013.01); C07C 2103/40 (2013.01); C07C 2103/54 (2013.01);
Abstract

The present disclosure is directed to a traceless directing group in a radical cascade. The chemo- and regioselectivity of the initial attack in skipped oligoalkynes is controlled by a propargyl alkoxy moiety. Radical translocations lead to the boomerang return of radical center to the site of initial attack where it assists to the elimination of the directing functionality via β-scission in the last step of the cascade. In some aspects, the reaction of the present invention is catalyzed by a stannane moiety, which allows further via facile reactions with electrophiles as well as Stille and Suzuki cross-coupling reactions. This selective radical transformation opens a new approach for the controlled transformation of skipped oligoalkynes into polycyclic ribbons of tunable dimensions.


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