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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9675672 B1

PDFFull Text
Expired
Date of Patent:
Jun. 13, 2017

Filed:

Sep. 11, 2015

Compositions and methods for modulating gamma-c-cytokine activity

Applicant:

Bioniz, Llc, Irvine, CA (US);

Inventors:

Yutaka Tagaya, Rockville, MD (US);

Nazli Azimi, San Juan Capistrano, CA (US);

Assignee:

BIONIZ, LLC, Irvine, CA (US);

Attorney:

Knobbe, Martens, Olson & Bear, LLP

Primary Examiner:

Julie Ha

Int. Cl.
CPC ...
A61K 38/10 (2006.01); A61K 38/20 (2006.01); A61K 47/00 (2006.01); A61K 8/64 (2006.01); A61Q 19/00 (2006.01); A61Q 19/08 (2006.01); A61Q 3/00 (2006.01); A61Q 7/00 (2006.01); C07K 14/52 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 38/20 (2013.01); A61K 8/64 (2013.01); A61K 47/48284 (2013.01); A61Q 3/00 (2013.01); A61Q 7/00 (2013.01); A61Q 19/00 (2013.01); A61Q 19/004 (2013.01); A61Q 19/08 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); C07K 14/52 (2013.01); A61K 38/10 (2013.01);
Abstract

The γc-family cytokines, Interleukin-2 (IL-2), Interleukin-4 (IL-4), Interleukin-7 (IL-7), Interleukin-9 (IL-9), Interleukin-15 (IL-15), and Interleukin-21 (IL-21), are associated with important human diseases, such as leukemia, autoimmune diseases, collagen diseases, diabetes mellitus, skin diseases, degenerative neuronal diseases and graft-versus-host disease (GvHD). Thus, inhibitors of γc-cytokine activity are valuable therapeutic and cosmetic agents as well as research tools. Peptide antagonists based on the consensus γc-subunit binding site to inhibit γc-cytokine activity are described. Also described are peptide antagonists exhibiting Simul-Block activity, and inhibiting the activity of multiple γc-cytokine family members.

Find Patent Forward Citations

Tagaya, Yutaka. (2017). Compositions and methods for modulating gamma-c-cytokine activity (U.S. Patent No. 9675672). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9675672

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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