The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 13, 2017
Filed:
Mar. 14, 2014
Applicant:
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
Amy Heimberger, Houston, TX (US);
Jun Wei, Houston, TX (US);
Assignee:
Board of Regents, The University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 31/7105 (2006.01); C12N 15/113 (2010.01); A61K 9/127 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7105 (2013.01); A61K 9/127 (2013.01); A61K 45/06 (2013.01); C12N 15/113 (2013.01);
Abstract
In some aspects, miRNA for the treatment of cancer are provided. In some embodiments, a miRNA (e.g., miR-124, miR-142, and/or miR-138) may be used to promote or enhance immune destruction of a cancer, or reduce the immune suppression of the cancer, in a subject. In other aspects, the miRNA may be used in, or in combination with, an adoptive immunotherapy.