The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 13, 2017
Filed:
May. 04, 2016
Applicant:
Pharmena Spólka Akcyjna (Pharmena S.a.), Lódz, PL;
Inventors:
Jerzy Gębicki, Lódz, PL;
Stefan Chłopicki, Cracow, PL;
Assignee:
Pharmena Spólka Akcyjna (Pharmena S.A.), Lodz, PL;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 31/455 (2006.01); A61K 31/4406 (2006.01); A61K 31/4425 (2006.01); A23L 33/00 (2016.01);
U.S. Cl.
CPC ...
A61K 31/455 (2013.01); A23L 33/30 (2016.08); A61K 9/007 (2013.01); A61K 9/0053 (2013.01); A61K 31/4406 (2013.01); A61K 31/4425 (2013.01);
Abstract
The invention relates to the use of quaternary pyridinium salts of formula (I), wherein R is NH, CH, or N(H)CHOH group, and X is pharmaceutically acceptable counterion, for the preparation of vasoprotective agent for the treatment or prevention of conditions or diseases associated with dysfunction of vascular endothelium, oxidative stress, and/or insufficient production of endothelial prostacyclin PGI, in particular but not exclusively if the above coincides with hypercholesterolemia, hypertriglyceridemia or low HDL level.