The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 13, 2017

Filed:

Sep. 21, 2015
Applicants:

Dominic Paul D'agostino, Tampa, FL (US);

Patrick Arnold, Champaign, IL (US);

Shannon Kesl, Tampa, FL (US);

Inventors:

Dominic Paul D'Agostino, Tampa, FL (US);

Patrick Arnold, Champaign, IL (US);

Shannon Kesl, Tampa, FL (US);

Assignee:

University of South Florida, Tampa, FL (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 37/02 (2006.01); A01N 37/06 (2006.01); A61K 31/225 (2006.01); A61K 31/23 (2006.01); A61K 31/19 (2006.01); A61K 31/20 (2006.01); A23L 2/52 (2006.01); A61K 31/047 (2006.01); A61K 31/22 (2006.01);
U.S. Cl.
CPC ...
A61K 31/23 (2013.01); A23L 2/52 (2013.01); A61K 31/047 (2013.01); A61K 31/19 (2013.01); A61K 31/20 (2013.01); A61K 31/22 (2013.01); A23V 2002/00 (2013.01);
Abstract

Beta-hydroxybutyrate mineral salts in combination with medium chain fatty acids or an ester thereof such as medium chain triglycerides were used to induce ketosis, achieving blood ketone levels of (2-7 mmol/L), with or without dietary restriction. The combination results in substantial improvements in metabolic biomarkers related to insulin resistance, diabetes, weight loss, and physical performance in a short period of time. Further, use of these supplements to achieve ketosis yields a significant elevation of blood ketones and reduction of blood glucose levels. Use of these substances does not adversely affect lipid profiles. By initiating rapid ketosis and accelerating the rate of ketoadaptation, this invention is useful for the avoidance of glucose withdrawal symptoms commonly experienced by individuals initiating a ketogenic diet, and minimizes the loss of lean body mass during dietary restriction.


Find Patent Forward Citations

Loading…