The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 13, 2017
Filed:
Aug. 28, 2014
Applicant:
The Cleveland Clinic Foundation, Cleveland, OH (US);
Inventors:
Anand Ramamurthi, Pepper Pike, OH (US);
Balakrishnan Sivaraman, Westlake, OH (US);
Andrew Sylvester, Richmond, VA (US);
Assignee:
The Cleveland Clinic Foundation, Cleveland, OH (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/48 (2006.01); A61K 9/51 (2006.01); A61K 9/14 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5153 (2013.01); A61K 9/14 (2013.01); A61K 47/48023 (2013.01); A61K 47/48915 (2013.01);
Abstract
Fibrinolytic nanoparticles including a polymeric core having a surface that is functionalized with a cationic amphiphilic compound, and a fibrinolytic agent dispersed within the core, are described herein. The fibrinolytic nanoparticles can be used in method of dissolving a blood clot in a subject by administering to the subject a therapeutically effective amount of fibrinolytic nanoparticles.